I am a final year PhD candidate in the Schnoor Lab of the Department of Molecular Biomedicine, CINVESTAV-IPN. I am investigating the role of the actin-binding protein cortactin in the onset and development of sepsis. Cortactin has been shown to support the transmigration of neutrophils across the endothelial barrier. Since sepsis-induced multi-organ damage is characterized by excessive neutrophil influx into peripheral organs such as the lung, we hypothesize that endothelial cortactin would regulate sepsis severity by controlling the recruitment of neutrophils into organs.
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